Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Phosphorylation Alters the Properties of Pol η: Implications for Translesion Synthesis
DNA polymerase ι is acetylated in response to SN2 alkylating agents | Scientific Reports
IJMS | Free Full-Text | Detours to Replication: Functions of Specialized DNA Polymerases during Oncogene-induced Replication Stress | HTML
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
DNA polymerases and cancer | Nature Reviews Cancer
Science Signaling - The DNA polymerase Pol-kappa endows tumor cells with resistance to the BRAF inhibitor vemurafenib without increasing mutagenesis, according to new research from the White lab. https://fcld.ly/5jaum2s Credit: K. Temprine
Translesion polymerase kappa-dependent DNA synthesis underlies replication fork recovery | eLife
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity
Inhibition of host NF-kappa-B by virus ~ ViralZone
Frontiers | Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms | ACS Chemical Biology
Regulation of the error-prone DNA polymerase Polκ by oncogenic signaling and its contribution to drug resistance | Science Signaling
A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ | PLOS ONE
A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells | Biochemistry
Anti-DNA Polymerase Kappa/POLK antibody (ab86076) | Abcam
Molecules | Free Full-Text | Mammalian DNA Polymerase Kappa Activity and Specificity | HTML
Frontiers | DNA Damage Tolerance Pathways in Human Cells: A Potential Therapeutic Target
DNA polymerase eta protects human cells against DNA damage induced by the tumor chemotherapeutic temozolomide - ScienceDirect
NF-κB inhibitors in treatment and prevention of lung cancer - ScienceDirect
Inhibition of Human DNA Polymerases Eta and Kappa by Indole-Derived Molecules Occurs through Distinct Mechanisms
NF-κB Signaling | NF-kappaB Pathway
DNA Polymerase Kappa Research Products: Novus Biologicals
