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The Role of Dynorphin and the Kappa Opioid Receptor in Schizophrenia and  Major Depressive Disorder: A Translational Approach | SpringerLink
The Role of Dynorphin and the Kappa Opioid Receptor in Schizophrenia and Major Depressive Disorder: A Translational Approach | SpringerLink

J Clin Med Res
J Clin Med Res

Opioid receptor modulation of neural circuits in depression: What can be  learned from preclinical data? - ScienceDirect
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect

Kappa Opioid System in Nucleus Accumbens Drives Pain-Induced Negative  Affect | Pain Research Forum
Kappa Opioid System in Nucleus Accumbens Drives Pain-Induced Negative Affect | Pain Research Forum

How Kappa Opioid Receptors Drive Anxiety – PsychLiverpool
How Kappa Opioid Receptors Drive Anxiety – PsychLiverpool

Frontiers | Dynorphin/kappa opioid receptor system regulation on amygdaloid  circuitry: Implications for neuropsychiatric disorders
Frontiers | Dynorphin/kappa opioid receptor system regulation on amygdaloid circuitry: Implications for neuropsychiatric disorders

Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and  Psychiatric Disorders: Function and Implications
Frontiers | The Role of the Kappa Opioid System in Comorbid Pain and Psychiatric Disorders: Function and Implications

Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain |  Journal of Neuroscience
Kappa Opioid Receptors Drive a Tonic Aversive Component of Chronic Pain | Journal of Neuroscience

Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class  of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink
Kappa Opioid Receptor Ligands and Pharmacology: Diphenethylamines, a Class of Structurally Distinct, Selective Kappa Opioid Ligands | SpringerLink

Frontiers Publishing Partnerships | Mechanisms Underlying the Anti-Suicidal  Treatment Potential of Buprenorphine
Frontiers Publishing Partnerships | Mechanisms Underlying the Anti-Suicidal Treatment Potential of Buprenorphine

Dynorphin/kappa-opioid receptor control of dopamine dynamics: Implications  for negative affective states and psychiatric disorders - ScienceDirect
Dynorphin/kappa-opioid receptor control of dopamine dynamics: Implications for negative affective states and psychiatric disorders - ScienceDirect

Chronic Kappa opioid receptor activation modulates NR2B: Implication in  treatment resistant depression | Scientific Reports
Chronic Kappa opioid receptor activation modulates NR2B: Implication in treatment resistant depression | Scientific Reports

Opioid receptor modulation of neural circuits in depression: What can be  learned from preclinical data? - ScienceDirect
Opioid receptor modulation of neural circuits in depression: What can be learned from preclinical data? - ScienceDirect

Frontiers | A Review of the Therapeutic Potential of Recently Developed G  Protein-Biased Kappa Agonists
Frontiers | A Review of the Therapeutic Potential of Recently Developed G Protein-Biased Kappa Agonists

Figure 4 | A Narrative Pharmacological Review of Buprenorphine: A Unique  Opioid for the Treatment of Chronic Pain | SpringerLink
Figure 4 | A Narrative Pharmacological Review of Buprenorphine: A Unique Opioid for the Treatment of Chronic Pain | SpringerLink

Frontiers | A Trigger for Opioid Misuse: Chronic Pain and Stress  Dysregulate the Mesolimbic Pathway and Kappa Opioid System
Frontiers | A Trigger for Opioid Misuse: Chronic Pain and Stress Dysregulate the Mesolimbic Pathway and Kappa Opioid System

κ Opioid Receptor-Dynorphin Signaling in the Central Amygdala Regulates  Conditioned Threat Discrimination and Anxiety | eNeuro
κ Opioid Receptor-Dynorphin Signaling in the Central Amygdala Regulates Conditioned Threat Discrimination and Anxiety | eNeuro

A systematic review on the kappa opioid receptor and its ligands: New  directions for the treatment of pain, anxiety, depression, and drug abuse -  ScienceDirect
A systematic review on the kappa opioid receptor and its ligands: New directions for the treatment of pain, anxiety, depression, and drug abuse - ScienceDirect

Opioids to Treat Depression: The Jury Is Out
Opioids to Treat Depression: The Jury Is Out

In major depression, increased kappa and mu opioid receptor levels are  associated with immune activation | Acta Neuropsychiatrica | Cambridge Core
In major depression, increased kappa and mu opioid receptor levels are associated with immune activation | Acta Neuropsychiatrica | Cambridge Core

Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands:  Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience
Signaling Properties of Structurally Diverse Kappa Opioid Receptor Ligands: Toward in Vitro Models of in Vivo Responses | ACS Chemical Neuroscience

Lowered endogenous mu-opioid receptor availability in subclinical depression  and anxiety | Neuropsychopharmacology
Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety | Neuropsychopharmacology

Development of κ opioid receptor antagonists. | Semantic Scholar
Development of κ opioid receptor antagonists. | Semantic Scholar

Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes  for the Kappa Opioid Receptor | Journal of Medicinal Chemistry
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor | Journal of Medicinal Chemistry

Dynorphin, stress, and depression | Semantic Scholar
Dynorphin, stress, and depression | Semantic Scholar

Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical  Role of the Dynorphin/Kappa Opioid Receptor System
Frontiers | Traumatic Stress-Induced Vulnerability to Addiction: Critical Role of the Dynorphin/Kappa Opioid Receptor System